Hmm look at this it seems when you feel full it’s actaully a drug that tells you to stop eating. Useful for making fat loss if used properly dont you think? From health.yahoo.com
“Scientists have identified a fatty substance made in the gut that signals the brain when it’s time to stop eating — a discovery that could inspire new approaches to fighting obesity.
Writing in the journal Cell on Wednesday, U.S. researchers said experiments with mice and rats showed that a naturally occurring fat-derived chemical messenger called NAPE regulated how much the animals ate. It is present in people and may do the same thing, they said.
Gerald Shulman of Yale University and the Howard Hughes Medical Institute and colleagues said that when the rodents were fed a fatty meal, their small intestine made a lot of NAPE and put it into the bloodstream. It then traveled to the brain and shut down hunger signals, they said.
NAPE levels shot up after the rodents ate a fatty meal, but not when they ate only protein or carbohydrates, they said.
The researchers then synthesized NAPE and injected it into the abdomen of the animals, whose appetites diminished greatly. When NAPE was delivered in much smaller amounts directly to the brain, it had the same effect on appetite as a larger dose injected into the bloodstream.”
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